MAGDA: A Mobile Agent based Grid Architecture

Mobile agents mean both a technology and a programming paradigm. They allow for a flexible approach which can alleviate a number of issues present in distributed and Grid-based systems, by means of features such as migration, cloning, messaging and other provided mechanisms. In this paper we describe an architecture (MAGDA – Mobile Agent based Grid Architecture) we have designed and we are currently developing to support programming and execution of mobile agent based application upon Grid systems

Surface doping in T6/ PDI-8CN2 Heterostructures investigated by transport and photoemission measurements

In this paper, we discuss the surface doping in sexithiophene (T6) organic field-effect transistors by PDI-8CN2. We show that an accumulation heterojunction is formed at the interface between the organic semiconductors and that the consequent band bending in T6 caused by PDI-8CN2 deposition can be addressed as the cause of the surface doping in T6 transistors. Several evidences of this phenomenon have been furnished both by electrical transport and photoemission measurements, namely the increase in the conductivity, the shift of the threshold voltage and the shift of the T6 HOMO peak towards higher binding energies.Comment: 5 pages, 5 figure

Effect of rear walls on the rocking response of rock blocks under seismic excitations

The rocking response of rigid free standing bodies subjected to seismic excitation has been studied by many researchers interested in different slender elements such as ancient stone columns, tombstones, rigid building structures. The extension of this model to rock mechanics has been proposed by a few authors. The rocking response of rectangular free standing bodies subjected to horizontal accelerations of natural recorded motions showed that the pseudo-static approach, based on Peak Ground Acceleration (PGA), permits only the determination of the uplift conditions and the beginning of rocking. It does not permit to evaluate the overturning of the blocks. The combined effect of vertical and horizontal seismic motions is negligible and, in some cases, beneficial. This paper presents a new mechanical model, called "one-sided rocking", that takes into account the presence of a rear rigid wall, that is a typical scenario for the rock blocks completely detached from the cliff but close to it. The dynamic response of a great number of rectangular rigid blocks, subjected to 62 recorded earthquake motions on rock soil (from US, Europe and Asia), has been analysed considering only the horizontal acceleration. The results show that the presence of the wall is detrimental for the rocking stability. However, there is still a safety reserve more significant for large blocks and rich frequency content time histories. This reserve could be taken into account in simplified (pseudo-static) analyses through reductive coefficient of PGA

BIOLOGICALLY STRUCTURED MATERIALS

Biomimetics, biomechanics, and tissue engineering are three multidisciplinary fields that have been contemplated in this research to attain the objective of improving prosthetic implants reliability. Since testing and mathematical methods are closely interlaced, a promising approach seemed to be the combination of in vitro and in vivo experiments with computer simulations (in silico). An innovative biomimetics and biomechanics approach, and a new synthetic structure providing a microenvironment, which is mechanically coherent and nutrient conducive for tissue osteoblast cell cultures used in regenerative medicine, are presented. The novel hybrid ceramic-polymeric nanocomposites are mutually investigated by finite element analysis (FEA) biomimetic modeling, anatomic reconstruction, quantitative-computed-tomography characterization, computer design of tissue scaffold. The starting base materials are a class of innovative highly bioactive hybrid ceramic-polymeric materials set-up by the proponent research group that will be used as a bioactive matrix for the preparation of in situ bio-mineralized techno- structured porous nanocomposites. This study treats biomimetics, biomechanics and tissue engineering as strongly correlated multidisciplinary fields combined to design bone tissue scaffolds. The growth, maintenance, and ossification of bone are fundamental and are regulated by the mechanical cues that are imposed by physical activities: this biomimetic/biomechanical approach will be pursued in designing the experimental procedures for in vitro scaffold mineralization and ossification. Bio-tissue mathematical modeling serves as a central repository to interface design, simulation, and tissue fabrication. Finite element computer analyses will be used to study the role of local tissue mechanics on endochondral ossification patterns, skeletal morphology and mandible thickness distributions using single and multi-phase continuum material representations of clinical cases of patients implanted with the traditional protocols. New protocols will be hypothesized for the use of the new biologically techno-structured hybrid materials

TRABECULAR PROSTHESES

The complex biomechanics and morphology of the femur proximal epiphysis are presented. This specific region in the human femur is characterized by high flexibility compared to that of other primates, since evolved lighter and longer due to the human vertical position and more balanced loading. The nature and fine morphology of the femur head and its structural behavior have been investigated. Isotropic and orthotropic trabecular structures, which are not present in other primates, have been associated with compression and tension areas of the femur head. These isotropic/orthotropic trabecular morphologies and allocations govern the stress and strain distribution in the overall proximal femur region. Use of femur proper biofidel modeling while enabling the explanation of physiological stress distribution elucidates the critical mechanical role of the trabecular bone that should be accounted in the design of a new innovative more "biologic" prosthetic system

A HIERARCHICAL DISTRIBUTED SHARED MEMORY PARALLEL BRANCH & BOUND APPLICATION WITH PVM AND OPENMP FOR MULTIPROCESSOR CLUSTERS

Branch&Bound (B&B) is a technique widely used to solve combinatorial optimization problems in physics and engineering science. In this paper we show how the combined use of PVM and OpenMP libraries can be a promising approach to exploit the intrinsic parallel nature of this class of application and to obtain efficient code for hybrid computational architectures. We described how both the shared memory and the distributed memory programming models can be applied to implement the same algorithm for the inter-nodes and intra-node parallelization. Some experimental tests on a local area network (LAN) of workstations are finally discussed

Jets and produced particles in pp collisions from SPS to RHIC energies for nuclear applications

Higher-order pQCD corrections play an important role in the reproduction of data at high transverse momenta in the energy range 20 GeV $\leq \sqrt{s} \leq 200$ GeV. Recent calculations of photon and pion production in $pp$ collisions yield detailed information on the next-to-leading order contributions. However, the application of these results in proton-nucleus and nucleus-nucleus collisions is not straightforward. The study of nuclear effects requires a simplified understanding of the output of these computations. Here we summarize our analysis of recent calculations, aimed at handling the NLO results by introducing process and energy-dependent $K$ factors.Comment: 4 pages with 5 eps figures include

Some aspects of the human body's hydraulics

This paper presents some aspects related to the human body's hydraulics in the desire to make readers aware of how to maintain all the blood vessels of the human body in order to maintain the entire healthy, functional, young, vigorous circulatory system for a while the longest possible. The problem is complex because it has to be viewed from all points of view and not only as an isolated system in the body, having aspects of feedback on the whole physiopathology belonging to the human body. The highly circulating system needs permanent maintenance. Self-maintenance is done through various physiological mechanisms tightly linked to each other, including the lymphatic, digestive, renal, lung, nervous, glandular system… It is not possible to completely separate the physiology of a system from the other adjacent systems because they all work synergistically, being permanently controlled by the central and peripheral nervous system

Impact of Chemical Endocrine Disruptors and Hormone Modulators on the Endocrine System

There is growing concern regarding the health and safety issues of endocrine-disrupting chemicals (EDCs). Long-term exposure to EDCs has alarming adverse health effects through both hormone-direct and hormone-indirect pathways. Non-chemical agents, including physical agents such as artificial light, radiation, temperature, and stress exposure, are currently poorly investigated, even though they can seriously affect the endocrine system, by modulation of hormonal action. Several mechanisms have been suggested to explain the interference of EDCs with hormonal activity. However, difficulty in quantifying the exposure, low standardization of studies, and the presence of confounding factors do not allow the establishment of a causal relationship between endocrine disorders and exposure to specific toxic agents. In this review, we focus on recent findings on the effects of EDCs and hormone system modulators on the endocrine system, including the thyroid, parathyroid glands, adrenal steroidogenesis, beta-cell function, and male and female reproductive function

Black hole and galaxy coevolution from continuity equation and abundance matching

We investigate the coevolution of galaxies and hosted supermassive black holes (BHs) throughout the history of the universe by a statistical approach based on the continuity equation and the abundance matching technique. Specifically, we present analytical solutions of the continuity equation without source terms to reconstruct the supermassive BH mass function from the active galactic nucleus (AGN) luminosity functions. Such an approach includes physically motivated AGN light curves tested on independent data sets, which describe the evolution of the Eddington ratio and radiative efficiency from slim- to thin-disk conditions. We nicely reproduce the local estimates of the BH mass function, the AGN duty cycle as a function of mass and redshift, along with the Eddington ratio function and the fraction of galaxies with given stellar mass hosting an AGN with given Eddington ratio. We exploit the same approach to reconstruct the observed stellar mass function at different redshift from the ultraviolet and far-IR luminosity functions associated with star formation in galaxies. These results imply that the build-up of stars and BHs in galaxies occurs via in situ processes, with dry mergers playing a ☉marginal role at least for stellar masses ≤ 3 × 1011 M☉ and BH masses 109 M where the statistical data are more secure and less biased by systematic errors. In addition, we develop an improved abundance matching technique to link the stellar and BH content of galaxies to the gravitationally dominant dark matter (DM) component. The resulting relationships constitute a testbed for galaxy evolution models, highlighting the complementary role of stellar and AGN feedback in the star formation process. In addition, they may be operationally implemented in numerical simulations to populate DM halos or to gauge subgrid physics. Moreover, they may be exploited to investigate the galaxy/AGN clustering as a function of redshift, mass, and/or luminosity. In fact, the clustering properties of BHs and galaxies are found to be in full agreement with current observations, thus further validating our results from the continuity equation. Finally, our analysis highlights that (i) the fraction of AGNs observed in the slim-disk regime, where most of the BH mass is accreted, increases with redshift; and (ii) already at z\gtrsim 6$ a substantial amount of dust must have formed over timescales 108 yr in strongly star-forming galaxies, making these sources well within the reach of ALMA surveys in (sub)millimeter bands